Author

Maria Roselle Abraham

University of California, San FranciscoORCID 0000-0002-7989-2210Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:scATAC-seq· 1

Frequent Co-Authors

Tilo ThottakaraiD· 2 shared Anja KarlstaedtiD· 1 shared Arpana Vaniya· 1 shared Arun PadmanabhaniD· 1 shared Carlin S. LongiD· 1 shared Damla Ates Gulkok· 1 shared Hannah Eades· 1 shared Hilary J. VernoniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Tilo ThottakaraORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Single-nucleus RNA/ATAC-seq Reveals SWI/SNF complex activation and allele-specific non-myocyte activation in HCM mouse models

Tilo Thottakara, Arun Padmanabhan, Talha Tanriverdi, Tharika Thambidurai, Jose A Diaz-Rg, Sanika Amonkar, Jeffrey E. Olgin, Carlin S. Long, Maria Roselle Abraham

The paper uses single-nucleus RNA/ATAC-seq to analyze HCM mouse models and identifies differences in gene expression and signaling pathways between mutant and wild-type hearts.

bioRxiv · Apr 24, 2024 · PreprintBioinformatics

Lipid metabolism drives allele-specific early-stage hypertrophic cardiomyopathy

Arpana Vaniya, Anja Karlstaedt, Damla Ates Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, Maria Roselle Abraham

This study identifies allele-specific metabolic differences in HCM mouse models, linking lipid metabolism to early-stage cardiac dysfunction.

bioRxiv · Nov 10, 2023 · PreprintSystems Biology