Author

Tilo Thottakara

Universität HamburgORCID 0000-0003-3862-1702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:scATAC-seq· 1

Frequent Co-Authors

Maria Roselle AbrahamiD· 2 shared Anja KarlstaedtiD· 1 shared Arpana Vaniya· 1 shared Arun PadmanabhaniD· 1 shared Carlin S. LongiD· 1 shared Damla Ates Gulkok· 1 shared Hannah Eades· 1 shared Hilary J. VernoniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Maria Roselle AbrahamORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 24, 2024

Single-nucleus RNA/ATAC-seq Reveals SWI/SNF complex activation and allele-specific non-myocyte activation in HCM mouse models

Tilo Thottakara, Arun Padmanabhan, Talha Tanriverdi…·Maria Roselle Abraham

The paper uses single-nucleus RNA/ATAC-seq to analyze HCM mouse models and identifies differences in gene expression and signaling pathways between mutant and wild-type hearts.

3 citations

mousescRNA-seq

𝕏 PostBluesky

Systems BiologybioRxivPreprintNov 10, 2023

Lipid metabolism drives allele-specific early-stage hypertrophic cardiomyopathy

Arpana Vaniya, Anja Karlstaedt, Damla Ates Gulkok…·Maria Roselle Abraham

This study identifies allele-specific metabolic differences in HCM mouse models, linking lipid metabolism to early-stage cardiac dysfunction.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky