Tanycyte-mediated synapse pruning shapes hypothalamic circuits controlling metabolism.
Rafik Dali, Irina Kolotuev, David López Rodríguez, Chaitanya K. Gavini, Tamara Déglise, Fanny Langlet
This study identifies tanycytes as glial cells that prune synapses in the hypothalamus, affecting metabolism and body weight control.
bioRxiv · Nov 14, 2025 · PreprintNeuroscience