Fanny Langlet

This study identifies tanycytes as glial cells that prune synapses in the hypothalamus, affecting metabolism and body weight control.

The paper identifies Annexin A1-containing extracellular vesicles from tanycytes that regulate thermogenesis and energy balance by modulating microglial and neuronal functions in obesity.

The paper analyzes hypothalamic ependymal cells using single-cell RNA sequencing to classify tanycyte subpopulations and reveal their functional heterogeneity under different fasting conditions.