Tan Maw Pin

Host transcriptional responses to gut microbiome variation arising from urbanism

The paper compares host transcriptional responses to urban and rural gut microbiomes, finding urban microbiomes affect innate immune pathways and high-diversity microbiomes trigger stronger host responses.

Convergent genomic responses of human gut bacteria to variations in industrialization

This study examines how gut bacteria genomes adapt to industrialization, finding convergent genomic responses in stress response, cell envelope remodeling, and central metabolism across different populations.

Industrialization drives convergent microbial and physiological shifts in the human metaorganism

The paper investigates how industrialization affects microbial and physiological traits in the human gut across diverse populations, finding homogenized microbiomes, reduced diversity, and impaired disease prediction accuracy in less industrialized groups.