Microtubule Acetylation Regulates the Malignant Phenotype of Glioblastoma and is a Promising Therapeutic Target
Natanael Zarco, Athanassios Dovas, Santanu Bhattacharya, Tanmay Kulkarni, Misha Amini, Yi Liu, Ashley N. Haddock, Naveen K H Nagaiah, Debrabrata Mukhopadhyay, Paola Suárez-Meade, Alfredo Quiñones‐Hinojosa, Courtney A. Miller, Theodore M. Kamenecka, Peter Canoll, Rajappa S. Kenchappa, Steven S. Rosenfeld
This study identifies ATAT1 as a therapeutic target in glioblastoma by showing its role in promoting tumor invasion, proliferation, and resistance, with potential for combination therapies.
bioRxiv · Jun 19, 2026 · PreprintCancer Biology