Peptide allosteric inhibitor of TNFR1 signaling attenuates inflammation and rheumatoid arthritis pathology in human TNF transgenic mice
Tanver Hasan Riyed, Kriti Kalary, Jialiu Zeng, Chih Hung Lo
This study evaluates a peptide-based inhibitor of TNFR1 signaling in a human TNF transgenic mouse model of RA, showing reduced inflammation and improved disease outcomes.
bioRxiv · Jul 4, 2026 · PreprintImmunology