Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression
Oswaldo A. Lozoya, Tianyuan Wang, Dagoberto Grenet, Taylor C. Wolfgang, Mack Sobhany, Douglas Ganini da Silva, Gonzalo Riadi, Navdeep S. Chandel, Richard P. Woychik, Janine Hertzog Santos
This study shows that mitochondrial acetyl-CoA reversibly modulates histone acetylation and gene expression in models of mtDNA depletion.
Life Science Alliance · Feb 1, 2019Peer-reviewedGenomics