Author

Taylor Cain

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:variant effect prediction· 2 Assay:whole-exome sequencing· 2 Approach:Bayesian inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Jamie L. MaciaszekiD· 2 shared Jeffery M. KlcoiD· 2 shared Mohammad K. EldomeryiD· 2 shared Patrick R. BlackburniD· 2 shared Victor Pastor Loyola· 2 shared Cai LiiD· 1 shared Chih-Hsuan Wu· 1 shared David A. WheeleriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Jamie L. MaciaszekORCID

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2 papers

Recent·Most cited

Prevalence and Clinical Significance of Adult-Onset Cancer Predisposition Variants in Pediatric Oncology

Jamie L. Maciaszek, Victor Pastor Loyola, Taylor Cain, Maria F. Cardenas, Patrick R. Blackburn, Mark R. Wilkinson, Selene C. Koo, Chih-Hsuan Wu, Cai Li, Lu Wang, Kim E. Nichols, Jeffery M. Klco, Mohammad K. Eldomery

The paper examines the prevalence and clinical significance of adult-onset cancer predisposition variants in pediatric cancer patients, finding most variants are secondary rather than directly related to the tumor.

medRxiv · Jun 8, 2026 · PreprintGenetic & Genomic Medicine

Evaluation of Bayesian Point-Based System on the Variant Classification of Hereditary Cancer Predisposition Genes

Mohammad K. Eldomery, Jamie L. Maciaszek, Taylor Cain, Victor Pastor Loyola, Suraj Sarvode Mothi, David A. Wheeler, Li Tang, Lu Wang, Jeffery M. Klco, Patrick R. Blackburn

The paper evaluates a Bayesian point-based system for variant classification in hereditary cancer genes, finding it reduces variants of uncertain significance compared to ACMG/AMP 2015 guidelines.

Genetics in Medicine · Sep 19, 2024Peer-reviewedGenetic & Genomic Medicine