Cai Li

The paper examines the prevalence and clinical significance of adult-onset cancer predisposition variants in pediatric cancer patients, finding most variants are secondary rather than directly related to the tumor.

The paper identifies that the helical bundle domain of human MIC60 is dispensable for its core functions, revealing unexpected modularity in MICOS organization.

Crop-OCT is an automated pipeline for analyzing OCT images to identify retinopathy in murine models, enabling the detection of regional and focal lesions across multiple diseases.

The paper examines neurometabolic correlates of accelerated aging and neurocognitive late effects in adult survivors of pediatric cancers using 1H MRS and cognitive tests.

The paper introduces a joint model with matching and regularization to detect OTU-specific compositional trajectories predictive of disease onset in metagenomic data.

The paper identifies 8 genetic variants associated with increased risk of COVID-19 mortality using UK Biobank data through a super-variant GWAS approach.