Protective efficacy of mutant strains of Borrelia burgdorferi as potential reservoir host-targeted biologics against Lyme disease
Venkatesh Kumaresan, Trever C. Smith, Miranda Lumbreras, Taylor MacMackin Ingle, Nathan Kilgore, Jolie F. Starling-Lin, Elizabeth J. Horn, Janakiram Seshu
This study evaluates non-infectious mutant strains of Borrelia burgdorferi and their lipoproteins as biologics to prevent Lyme disease transmission by reducing bacterial acquisition in ticks.
Infection and Immunity · Jun 3, 2026Peer-reviewedMicrobiology