Trever C. Smith

This study evaluates non-infectious mutant strains of Borrelia burgdorferi and their lipoproteins as biologics to prevent Lyme disease transmission by reducing bacterial acquisition in ticks.

This study introduces DECIPHAER, a tool that identifies critical mechanisms of tuberculosis drug action by integrating multi-modal data, revealing that respiration inhibition is more impactful than cell wall effects.

This study shows that Mycobacterium tuberculosis adapts to acidic conditions by increasing growth-arrested cells, which enhance drug tolerance and survival.