Mutations in conserved residues of the myosin chaperone UNC-45 result in both reduced stability and chaperoning activity
Taylor Moncrief, Courtney J. Matheny, Ivana Gažiová, John M. Miller, Hiroshi Qadota, Guy M. Benian, Andrés F. Oberhauser
The paper investigates how mutations in UNC-45/UNC-45B affect myosin chaperone activity and protein stability in C. elegans, finding reduced chaperone activity and protein levels in most mutants.
Protein Science · Sep 13, 2021Peer-reviewedMolecular Biology