Molecular BiologyProtein SciencePeer-reviewed
Mutations in conserved residues of the myosin chaperone UNC-45 result in both reduced stability and chaperoning activity
Taylor Moncrief, Courtney J. Matheny, Ivana Gažiová…·Andrés F. Oberhauser
The paper investigates how mutations in UNC-45/UNC-45B affect myosin chaperone activity and protein stability in C. elegans, finding reduced chaperone activity and protein levels in most mutants.
10 citations