Hiroshi Qadota

The paper shows that the PX domain of RRC-1 is necessary for its localization to muscle cell boundaries and for proper integrin adhesion complex assembly and function in C. elegans.

This study investigates the substrate targeting and functional role of twitchin kinase (TwcK) in C. elegans muscle, revealing its moonlighting role and distinct activation mechanism.

This paper identifies ipmk-1 as a genetic enhancer of the PIX-1 pathway in C. elegans muscle, showing that PIP3 and PIP2 levels affect integrin adhesion complex assembly.

This study shows that in aging mouse hearts, Unc45b and Hsp70 levels decline at the protein level, while Hsp90 remains stable, potentially contributing to age-related cardiomyopathies.

The paper identifies a surface on PAT-4 that interacts with UNC-112 through genetic analysis in C. elegans.

The paper investigates how mutations in UNC-45/UNC-45B affect myosin chaperone activity and protein stability in C. elegans, finding reduced chaperone activity and protein levels in most mutants.