Basal stem cell fate specification is mediated by SMAD signaling in the developing human lung
Alyssa J. Miller, Qianhui Yu, Michael J. Czerwinski, Yu-Hwai Tsai, Renee F. C. Hein, Angeline Wu, Emily M. Holloway, Taylor Walker, Ian A. Glass, Barbara Treutlein, J. Gray Camp, Jason R. Spence
The paper identifies SMAD signaling as a regulator of basal cell fate specification in the developing human lung using single-cell transcriptomics and organoid models.
Developmental Cell · Feb 27, 2020Peer-reviewedDevelopmental Biology