Characterization of a Biochemical Mouse Model of Primary Aldosteronism for Thermal Therapies
Sarah A. Timmerman, Nathan Mullen, ANGELA E. R. TAYLOR, Lorna C Gilligan, Marla M. Pyle, Tej B. Shrestha, Jan Šebek, Margaret A. Highland, Ritihaas Surya Challapalli, Wiebke Arlt, Stefan H. Bossmann, Michael Conall Dennedy, Punit Prakash, Matthew T. Basel
The paper develops a mouse model of aldosterone-producing adenoma to test thermal ablation therapies, showing reduced aldosterone production after treatment.
bioRxiv · May 7, 2024 · PreprintCancer Biology