Inhibitor of the spindle assembly checkpoint surpasses apoptosis sensitizer in synergy with taxanes
Teng-Long Han, Zhi-Xin Jiang, Yun-Tian Li, Deng-Shan Wu, Jun Ji, Hu Lin, Bin Hu, Hang Sha
This study shows that inhibiting the spindle assembly checkpoint (SAC) is more effective than apoptosis sensitizers in enhancing taxane-induced tumor cell growth arrest.
bioRxiv · Sep 11, 2018 · PreprintCancer Biology