Evolutionary BiologybioRxiv
On the evolutionary ecology of multidrug resistance in bacteria
S. Lehtinen, F. Blanquart, M. Lipsitch…·The Maela Pneumococcal Collaboration
This paper explains high multidrug resistance frequencies in bacteria through ecological models of strain competition, showing that resistance to different antibiotics often co-occurs due to stable coexistence rather than competitive exclusion.
DOI 10.1371/journal.ppat.1007763