Author

Thomas A. Hamilton

Western University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Benjamin R. JorisiD· 2 shared David R. EdgelliD· 2 shared Gregory Brian GlooriD· 2 shared Tyler S. BrowneiD· 2 shared Arina Shrestha· 1 shared Bogumil Jacek KarasiD· 1 shared Sébastien RodrigueiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersSynthetic Biology

Benjamin R. JorisORCID

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Author profile →

2 papers

Recent·Most cited

De novo synthesis of a conjugative system from human gut metagenomic data for targeted delivery of Cas9 antimicrobials

Thomas A. Hamilton, Benjamin R. Joris, Arina Shrestha, Tyler S. Browne, Sébastien Rodrigue, Bogumil Jacek Karas, Gregory Brian Gloor, David R. Edgell

ACS Synthetic Biology · Dec 4, 2023Peer-reviewedSynthetic Biology

Separation of cohorts on the basis of bacterial type IV conjugation systems identified from metagenomic assemblies

Benjamin R. Joris, Tyler S. Browne, Thomas A. Hamilton, David R. Edgell, Gregory Brian Gloor

The paper identifies type IV conjugation systems in metagenomic data and shows they differ between age and geographic cohorts, suggesting their use as biomarkers and highlighting limitations of current binning methods.

bioRxiv · Apr 15, 2021 · PreprintBioinformatics