Maternal diet-induced obesity during pregnancy alters lipid supply to fetuses and changes the cardiac tissue lipidome in a sex- dependent manner
Lucas C. Pantaleão, Isabella Inzani, Samuel Furse, Elena Loche, Antonia Hufnagel, Thomas J. Ashmore, Heather L. Blackmore, Benjamin Jenkins, Asha A. M. Carpenter, Ania Wilczynska, Martin Bushell, Albert Koulman, Denise S. Fernandez‐Twinn, Susan Elizabeth Ozanne
This study shows maternal diet-induced obesity alters fetal cardiac lipidomes and serum lipidomes differently in male and female fetuses, with female hearts showing greater sensitivity.
eLife · Jan 13, 2022Peer-reviewedDevelopmental Biology