Susan Elizabeth Ozanne

This study develops an ovine model of maternal diet-induced obesity during pregnancy and finds fetal sex-specific changes in uterine vascular function.

The paper identifies rare genetic variants associated with birth weight, highlighting genes involved in adipose tissue regulation, placental function, and insulin-like growth factor signaling.

The paper examines evolutionary potential and phenotypic plasticity in rat molars, finding that later-developing molars are equally or more evolvable than earlier ones, despite increased developmental instability.

The paper identifies chromatin loop rewiring in adipogenesis and discovers novel regulators and gene-trait associations relevant to obesity and diabetes.

This study identifies Mir483 as a growth suppressor and metabolic regulator that antagonizes its host gene Igf2 through IGF1 signaling, revealing a novel mechanism of growth control.

This study shows maternal diet-induced obesity alters fetal cardiac lipidomes and serum lipidomes differently in male and female fetuses, with female hearts showing greater sensitivity.

The paper uses small-RNA sequencing to identify altered microRNA and snoRNA signatures in skeletal muscle of male mouse offspring from dams with low protein diets during lactation.

This study identifies mesenchymal Igf2 as a critical paracrine regulator of pancreatic growth and function through in vivo and ex vivo experiments.