Author

Denise S. Fernandez‐Twinn

University of CambridgeORCID 0000-0003-2610-277XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Susan Elizabeth OzanneiD· 4 shared Ionel SandoviciiD· 2 shared John R. B. PerryiD· 2 shared Katherine A. KentistouiD· 2 shared Ken K. OngiD· 2 shared Lucas C. PantaleãoiD· 2 shared Martin BushelliD· 2 shared Miguel ConstânciaiD· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersDevelopmental Biology

Susan Elizabeth OzanneORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GeneticsbioRxivPreprintJun 27, 2023

Rewiring of chromatin loops in adipogenesis reveals targets for obesity and diabetes intervention

Ionel Sandovici, Borbála Mifsud, Katherine A. Kentistou…·Miguel Constância

The paper identifies chromatin loop rewiring in adipogenesis and discovers novel regulators and gene-trait associations relevant to obesity and diabetes.

1 citation

humanChIP-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintSep 9, 2022

The imprinted Mir483 is a growth suppressor and metabolic regulator functioning through IGF1

Ionel Sandovici, Denise S. Fernandez‐Twinn, Niamh Campbell…·Miguel Constância

This study identifies Mir483 as a growth suppressor and metabolic regulator that antagonizes its host gene Igf2 through IGF1 signaling, revealing a novel mechanism of growth control.

DOI 10.1101/2022.09.09.507324

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 1, 2022

Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food

Laura Dearden, Isadora C. Furigo, Lucas C. Pantaleão…·Susan Elizabeth Ozanne

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyeLifePeer-reviewedJan 13, 2022

Maternal diet-induced obesity during pregnancy alters lipid supply to fetuses and changes the cardiac tissue lipidome in a sex- dependent manner

Lucas C. Pantaleão, Isabella Inzani, Samuel Furse…·Susan Elizabeth Ozanne

This study shows maternal diet-induced obesity alters fetal cardiac lipidomes and serum lipidomes differently in male and female fetuses, with female hearts showing greater sensitivity.

19 citationstop 4%

mousebulk RNA-seq

𝕏 PostBluesky