Author

Thomas M Leibiger

University of Delaware

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Biology Disciplines

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Bioengineering· 1

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Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Eleftherios Terry PapoutsakisiD· 1 shared Jayanth Venkatarama ReddyiD· 1 shared Kelvin H. LeeiD· 1 shared Marianthi IerapetritouiD· 1 shared Sumit Kumar SinghiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBioengineering

Eleftherios Terry PapoutsakisORCID

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1 paper

Recent·Most cited

Flux balance analysis and peptide mapping elucidate the impact of bioreactor pH on Chinese Hamster Ovary (CHO) cell metabolism and N-linked glycosylation in the Fab and Fc regions of the produced IgG

Jayanth Venkatarama Reddy, Sumit Kumar Singh, Thomas M Leibiger, Kelvin H. Lee, Marianthi Ierapetritou, Eleftherios Terry Papoutsakis

This study examines how bioreactor pH affects CHO cell metabolism and N-linked glycosylation of IgG antibodies using flux balance analysis and glycopeptide mapping.

Metabolic Engineering · Aug 2, 2024Peer-reviewedBioengineering