BioengineeringMetabolic EngineeringPeer-reviewed
Flux balance analysis and peptide mapping elucidate the impact of bioreactor pH on Chinese Hamster Ovary (CHO) cell metabolism and N-linked glycosylation in the Fab and Fc regions of the produced IgG
Jayanth Venkatarama Reddy, Sumit Kumar Singh, Thomas M Leibiger…·Eleftherios Terry Papoutsakis
This study examines how bioreactor pH affects CHO cell metabolism and N-linked glycosylation of IgG antibodies using flux balance analysis and glycopeptide mapping.
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