Author

Thu Lan Nguyen

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Marie‐Christine BirlingiD· 2 shared Véronique BraultiD· 2 shared Yann HéraultiD· 2 shared Aline DubosiD· 1 shared Antigoni ManousopoulouiD· 1 shared Eugene Y. YuiD· 1 shared Gabrielle RudolfiD· 1 shared Giovanni Lo IaconoiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersDevelopmental Biology

Marie‐Christine BirlingORCID

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2 papers

Recent·Most cited

Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

María-Victoria Hinckelmann, Aline Dubos, Victorine Artot, Gabrielle Rudolf, Thu Lan Nguyen, Peggy Tilly, Valérie Nalesso, Maria del Mar Muñiz Moreno, Marie‐Christine Birling, Juliette D. Godin, Véronique Brault, Yann Hérault

This study shows that Dyrk1a regulates interneuron migration via actomyosin dynamics, leading to cortical GABAergic system defects and phenotypes seen in DYRK1A-haploinsufficiency syndrome.

bioRxiv · Nov 9, 2023 · PreprintDevelopmental Biology

Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome

Véronique Brault, Thu Lan Nguyen, Javier Flores Gutiérrez, Giovanni Lo Iacono, Marie‐Christine Birling, Valérie Lalanne, Hamid Méziane, Antigoni Manousopoulou, Guillaume Pavlovic, Loïc Lindner, Mohammed Selloum, Tania Sorg, Eugene Y. Yu, Spiros D. Garbis, Yann Hérault

This study investigates the effects of Dyrk1a gene dosage in glutamatergic neurons on cognitive deficits in MRD7 and Down syndrome mouse models, finding specific roles in long-term explicit memory.

PLoS Genetics · Sep 29, 2021Peer-reviewedNeuroscience