Author

Timothy Billings

Jackson Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Petko M. PetkoviD· 4 shared Michael Walker· 2 shared Catrina Spruce· 1 shared Christopher L. BakeriD· 1 shared Emil D. Parvanov· 1 shared Gary D. StormoiD· 1 shared Hui TianiD· 1 shared Hui Tian· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersGenetics

Petko M. PetkovORCID

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4 papers

Recent·Most cited

Quantitative analysis of ZFY and CTCF reveals dependent recognition of tandem zinc finger proteins.

Zheng Zuo, Timothy Billings, Michael Walker, Petko M. Petkov, Polly Morrell Fordyce, Gary D. Stormo

The paper quantifies how tandem zinc fingers in ZFY, CTCF, and ZNF343 recognize DNA motifs, showing dependent recognition and non-additive specificity.

Nucleic Acids Research · Mar 14, 2023Peer-reviewedGenetics

Differential effects of two catalytic mutations on full-length PRDM9 and its isolated PR/SET domain reveal a case of pseudo-modularity

Natalie R. Powers, Timothy Billings, Kenneth Paigen, Petko M. Petkov

The paper examines two catalytic mutations in PRDM9, showing they affect methyltransferase activity differently in full-length versus isolated PR/SET domain, revealing non-modular behavior.

Genetics · Oct 9, 2021Peer-reviewedGenetics

EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis

Hui Tian, Timothy Billings, Michael Walker, Petko M. Petkov, Christopher L. Baker

The paper shows EWSR1 is essential for PRDM9-dependent histone methylation and linking recombination hotspots to the chromosome axis during meiosis.

Molecular Biology of the Cell · Nov 11, 2020Peer-reviewedDevelopmental Biology

PRDM9 forms a multiprotein complex tethering recombination hotspots to the chromosomal axis

Emil D. Parvanov, Hui Tian, Timothy Billings, Ruth L. Saxl, Catrina Spruce, Rakesh Aithal, Lumir Krejci, Kenneth Paigen, Petko M. Petkov

The paper identifies proteins that form a complex with PRDM9 to tether recombination hotspots to the chromosomal axis during meiosis.

bioRxiv · Sep 16, 2016 · PreprintCell Biology