Author

Natalie R. Powers

Jackson LaboratoryORCID 0000-0001-6313-1719Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Kenneth PaigeniD· 3 shared Petko M. PetkoviD· 3 shared Beth L. DumontiD· 1 shared Bo JiiD· 1 shared Catherine BruntoniD· 1 shared Catrina A. SpruceiD· 1 shared Chihiro EmoriiD· 1 shared Christopher L. BakeriD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersGenetics

Kenneth PaigenORCID

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3 papers

Recent·Most cited

GeneticsGeneticsPeer-reviewedOct 9, 2021

Differential effects of two catalytic mutations on full-length PRDM9 and its isolated PR/SET domain reveal a case of pseudo-modularity

Natalie R. Powers, Timothy Billings, Kenneth Paigen, Petko M. Petkov

The paper examines two catalytic mutations in PRDM9, showing they affect methyltransferase activity differently in full-length versus isolated PR/SET domain, revealing non-modular behavior.

2 citations

mouseproteomics

𝕏 PostBluesky

GeneticsScience AdvancesPeer-reviewedOct 23, 2020

Sexual dimorphism in the meiotic requirement for PRDM9: a mammalian evolutionary safeguard

Natalie R. Powers, Beth L. Dumont, Chihiro Emori…·Tanmoy Bhattacharyya

The paper shows that sex-specific modifiers, like CHK2, allow female fertility without PRDM9, revealing sex-specific regulation of meiotic recombination.

18 citations

mousestatistical model

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GenomicsGeneticsPeer-reviewedDec 28, 2018

Tissue-specific trans regulation of the mouse epigenome

Christopher L. Baker, Michael Walker, Seda Arat…·Kenneth Paigen

The paper identifies tissue-specific trans-regulation of H3K4me3 levels in mouse cell types and links it to histone quantitative trait loci (hQTL) associated with zinc finger genes.

19 citations

mouseChIP-seq

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