Growth and patterning in vertebrate limb developmentA timescale perspective on skeletal specification
Soha Ben Tahar, Ester Comellas, Timothy Duerr, Dareen Bakr, James R. Monaghan, José J. Muñoz, Sandra J. Shefelbine
This paper introduces a computational framework to model limb skeletal patterning in mice and axolotls by integrating growth, gene regulation, and signaling spread, showing varying contributions of these factors across limb regions.
PLoS Computational Biology · Jul 7, 2026Peer-reviewedDevelopmental Biology