José J. Muñoz

Why is the purse string not enough?

The paper uses a 3D biophysical model to show that cell aspect ratio affects purse string efficiency in wound closure, with taller cells being more deformable and squamous cells requiring stronger purse strings.

Growth and patterning in vertebrate limb developmentA timescale perspective on skeletal specification

This paper introduces a computational framework to model limb skeletal patterning in mice and axolotls by integrating growth, gene regulation, and signaling spread, showing varying contributions of these factors across limb regions.

Three-Dimensional Mechanical Cooperativity Optimises Epithelial Wound Healing

This study identifies a 3D mechanical mechanism in Drosophila wing disc epithelia that enhances wound healing through coordinated cell shape changes and intercalations.

Neural sensing of surface traction modulates proprioceptive activity and locomotion in Caenorhabditis elegans

This study shows that touch receptors in C. elegans detect surface traction, influencing proprioception and locomotion through MEC-4 channel activity and friction force.

Turing pattern prediction in three-dimensional domains: the role of initial conditions and growth

This study investigates Turing pattern formation in 3D domains, showing that initial conditions and domain growth influence pattern stability and emergence.

Local mechanical stimuli shape tissue growth in vertebrate joint morphogenesis

The paper investigates how mechanical stimuli influence joint morphogenesis by combining experimental and computational approaches in axolotl limb regeneration.

Condensation of the Drosophila Nerve Cord is Oscillatory and depends on Coordinated Mechanical Interactions

The paper investigates the mechanics of Drosophila ventral nerve cord condensation, revealing oscillatory contractions and coordinated mechanical interactions between neurons and glia.