Automated and accurate estimation of gene family abundance from shotgun metagenomes
Stephen Nayfach, Patrick H. Bradley, Stacia K. Wyman, Timothy J. Laurent, Alex Williams, Jonathan A. Eisen, Katherine S. Pollard, Thomas J. Sharpton
This paper develops ShotMAP, a metagenome annotation pipeline, and evaluates its performance on marine and gut microbiome data, finding functional differences in Crohn's disease patients.
bioRxiv · Jul 10, 2015Bioinformatics