Author

Alex Williams

Brigham and Women's HospitalPrimary ORCID profile (0000-0003-3894-304X · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Alex WilliamsiD3 papers · University of Sheffield

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ahmed EdrisiD· 1 shared Anna L. GuyattiD· 1 shared Ashmita KciD· 1 shared Balasubramanya Seetharama Rao· 1 shared Calum A. MacRaeiD· 1 shared Dajun QuaniD· 1 shared Edward J. HolloxiD· 1 shared Emily PaniD· 1 shared

Activity by Year

2015-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Ahmed EdrisORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Beyond Glycogen Storage: AMPKγ2 Regulates Cardiac Hypertrophy and Electrophysiology via Myosin Interaction

Qianyun Ge, Kusumika Saha, Micah L. Burch, Willow H. Battista, Ashmita Kc, Max Homilius, Rachelle A. Victorio, Dajun Quan, Hsiang-Ling Huang, Joseph M. Hazel, Alex Williams, Emily Pan, Krishna Chinthalapudi, Sarah M. Heissler, Calum A. MacRae, Wandi Zhu

This study shows PRKAG2 variants cause cardiac hypertrophy and electrical changes in zebrafish, independent of glycogen storage, through AMPKγ2-myosin interactions.

bioRxiv · Apr 23, 2026 · PreprintPhysiology

DeepPheWAS: an R package for phenotype generation and association analysis for phenome-wide association studies.

Richard J. Packer, Alex Williams, William Hennah, Micaela Eisenberg, Nick R. G. Shrine, Katherine A. Fawcett, Willow Pearson, Anna L. Guyatt, Ahmed Edris, Edward J. Hollox, Mikko Marttila, Balasubramanya Seetharama Rao, John Raymond Bratty, Louise V. Wain, Frank Dudbridge, Martin D. Tobin

DeepPheWAS creates composite phenotypes and performs association analysis for phenome-wide studies using genetic inputs and various models.

Bioinformatics · Feb 4, 2023Peer-reviewedGenetic & Genomic Medicine

Automated and accurate estimation of gene family abundance from shotgun metagenomes

Stephen Nayfach, Patrick H. Bradley, Stacia K. Wyman, Timothy J. Laurent, Alex Williams, Jonathan A. Eisen, Katherine S. Pollard, Thomas J. Sharpton

This paper develops ShotMAP, a metagenome annotation pipeline, and evaluates its performance on marine and gut microbiome data, finding functional differences in Crohn's disease patients.

bioRxiv · Jul 10, 2015Bioinformatics