Expanding the CITE-seq tool-kit: Detection of proteins, transcriptomes, clonotypes and CRISPR perturbations with multiplexing, in a single assay
Eleni P. Mimitou, Anthony Youzhi Cheng, Antonino Montalbano, Stephanie Hao, Marlon Stoeckius, Mateusz Legut, Timothy Roush, Alberto M. Herrera, Efthymia Papalexi, Zeping Ouyang, Rahul Satija, Neville E. Sanjana, Sergei B. Koralov, Peter Smibert
The paper introduces ECCITE-seq, a method that simultaneously captures transcriptomes, immune clonotypes, surface markers, sample identity, and CRISPR perturbations from single cells.
bioRxiv · Nov 8, 2018 · PreprintGenomics