Author

Antonino Montalbano

New York Genome CenterORCID 0000-0002-7824-342XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:benchmarking· 2 Organism:human· 2 Research Focus:perturbation response prediction· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Neville E. SanjanaiD· 2 shared Peter SmibertiD· 2 shared Akash Sookdeo· 1 shared Alberto M. HerreraiD· 1 shared Alejandro Méndez‐MancillaiD· 1 shared Anthony Youzhi ChengiD· 1 shared Chia-Yu Kung· 1 shared Efthymia PapalexiiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

Neville E. SanjanaORCID

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Author profile →

3 papers

Recent·Most cited

Cutting Through the Artifacts: Dissecting gRNA Impurities with FUSS-seq

Antonino Montalbano, Huan Qiu, Lakshmi Karthik, Sawyer Letourneau, Jianxin Hu, Tirtha Chakraborty, Huanying Gary Ge, John R. Lydeard, Ruijia Wang, Eric Gunnar Anderson

The paper identifies sequencing artifacts in gRNA purity assessment and introduces FUSS-seq to reduce them, improving accuracy for CRISPR-based therapeutics.

bioRxiv · Sep 13, 2025 · PreprintMolecular Biology

Scalable pooled CRISPR screens with single-cell chromatin accessibility profiling

Noa Liscovitch‐Brauer, Antonino Montalbano, Jiale Deng, Alejandro Méndez‐Mancilla, Hans‐Hermann Wessels, Nicholas G. Moss, Chia-Yu Kung, Akash Sookdeo, Xinyi Guo, Evan T. Geller, Suma Jaini, Peter Smibert, Neville E. Sanjana

This paper introduces CRISPR-sciATAC, a method linking genetic perturbations to chromatin accessibility in single cells, showing its effectiveness in human and mouse experiments.

Nature Biotechnology · Apr 29, 2021Peer-reviewedGenomics

Expanding the CITE-seq tool-kit: Detection of proteins, transcriptomes, clonotypes and CRISPR perturbations with multiplexing, in a single assay

Eleni P. Mimitou, Anthony Youzhi Cheng, Antonino Montalbano, Stephanie Hao, Marlon Stoeckius, Mateusz Legut, Timothy Roush, Alberto M. Herrera, Efthymia Papalexi, Zeping Ouyang, Rahul Satija, Neville E. Sanjana, Sergei B. Koralov, Peter Smibert

The paper introduces ECCITE-seq, a method that simultaneously captures transcriptomes, immune clonotypes, surface markers, sample identity, and CRISPR perturbations from single cells.

bioRxiv · Nov 8, 2018 · PreprintGenomics