Meiotic viral attenuation through an ancestral apoptotic pathway
Jie Gao, Sabrina Chau, Fuad Chowdhury, Tina Zhou, Saif Hossain, G. Angus McQuibban, Marc D. Meneghini
This study shows that budding yeast uses a mitochondrial endonuclease homologue to attenuate a cytosolic virus during meiosis, revealing an ancestral role for apoptotic pathways in viral defense.
Proceedings of the National Academy of Sciences · Jul 2, 2019Peer-reviewedGenetics