Author

Jie Gao

University of TorontoORCID 0000-0002-3765-306XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jie Gao4 papers · Chinese PLA General Hospital

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Marc D. MeneghiniiD· 2 shared Sabrina ChauiD· 2 shared Braden Martyn· 1 shared Brittney Remnant· 1 shared Fuad ChowdhuryiD· 1 shared G. Angus McQuibbaniD· 1 shared Jing Li· 1 shared Mark A. BayfieldiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Marc D. MeneghiniORCID

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2 papers

Recent·Most cited

Endonuclease G governs an antiviral RNA surveillance system in budding yeast

Jie Gao, Brittney Remnant, Braden Martyn, Minyoung Chung, Jing Li, Megan Pickett, Sabrina Chau, Mark A. Bayfield, Marc D. Meneghini

This study identifies Nuc1, a mitochondrial enzyme, as a regulator of an RNA surveillance system in yeast that limits replication of the L-A mycovirus.

bioRxiv · Oct 30, 2026 · PreprintMolecular Biology

Meiotic viral attenuation through an ancestral apoptotic pathway

Jie Gao, Sabrina Chau, Fuad Chowdhury, Tina Zhou, Saif Hossain, G. Angus McQuibban, Marc D. Meneghini

This study shows that budding yeast uses a mitochondrial endonuclease homologue to attenuate a cytosolic virus during meiosis, revealing an ancestral role for apoptotic pathways in viral defense.

Proceedings of the National Academy of Sciences · Jul 2, 2019Peer-reviewedGenetics