RNA polymerase I transcription fidelity, speed and processivity depend on the interplay of its lobe binding subunits
Philipp E. Merkl, Michael Pilsl, Tobias Fremter, Gernot Längst, Philipp Milkereit, Joachim Griesenbeck, Herbert Tschochner
The paper investigates how the lobe-binding module of RNA polymerase I affects transcription fidelity, speed, and processivity in vitro, showing its unique ability to transcribe nucleosomal templates compared to Pol II.
bioRxiv · Oct 2, 2018 · PreprintBiochemistry