Gernot Längst

The SWI/SNF subunit SWI3B functions with the m6A writer complex to establish embryo patterning in Arabidopsis

This paper identifies SWI3B as an interactor of the m6A methyltransferase MTA in Arabidopsis, showing their cooperative role in embryo patterning by regulating transcript stability and expression patterns.

Deciphering chromatin architecture and dynamics in Plasmodium falciparum using the nucDetective pipeline

The paper develops a pipeline to analyze chromatin structure in Plasmodium falciparum and shows that its chromatin has a regular structure with stage-specific changes.

RNA-DNA triplex-forming miRNAs define an evolutionarily recent chromatin regulatory mechanism

The paper identifies RNA-DNA triplex-forming miRNAs in human cells and shows they are evolutionarily recent and associated with Ago2-chromatin interactions.

Adenovirus maturation establishes the transcription competent packaging of its genome

This study identifies genomic regions that become decompacted during adenovirus maturation, revealing how DNA sequence features guide genome organization for transcription.

The RALF Signaling Pathway Regulates Cell Wall Integrity during Pollen Tube Growth in Maize

The study identifies the role of Clade IB ZmRALF2/3 in regulating cell wall integrity during maize pollen tube growth through interactions with receptor kinases, co-receptors, and cell wall proteins.

nucMACC: A MNase-seq pipeline to identify structurally altered nucleosomes in the genome

nucMACC is a MNase-seq pipeline that identifies structurally altered nucleosomes by analyzing nucleosome accessibility and stability in D. melanogaster and S. cerevisiae.

HMGN5, an RNA or Nucleosome binding protein - potentially switching between the substrates to regulate gene expression

This paper identifies HMGN5 as a chromatin and RNA binding protein that switches between substrates to regulate gene expression by interacting with nucleosomes and RNA.

Characterizing higher order structures of chromatin in human cells

The paper investigates chromatin organization using MNase-seq and finds no evidence of differentially compacted domains, supporting an irregular model of large-scale chromatin structure.

RNA polymerase I transcription fidelity, speed and processivity depend on the interplay of its lobe binding subunits

The paper investigates how the lobe-binding module of RNA polymerase I affects transcription fidelity, speed, and processivity in vitro, showing its unique ability to transcribe nucleosomal templates compared to Pol II.