Proteomic and structural comparison between cilia from primary ciliary dyskinesia patients with a DNAH5 defect
Charlotte de Ceuninck van Capelle, Leo Luo, Alexander Leitner, Stefan A. Tschanz, Philipp Latzin, Sebastian R. Ott, Tobias Herren, Loretta L. Müller, Takashi Ishikawa
The paper compares proteomic and structural differences in cilia from PCD patients with DNAH5 mutations, showing patient-specific reductions in ciliary components and structural changes in the axoneme.
Frontiers in Molecular Biosciences · Jul 17, 2025Peer-reviewedCell Biology