Leo Luo

This paper enhances the spatial resolution of soft X-ray tomography using physics-aware learning, improving structural fidelity and reducing radiation exposure.

The paper compares proteomic and structural differences in cilia from PCD patients with DNAH5 mutations, showing patient-specific reductions in ciliary components and structural changes in the axoneme.

The paper investigates protein interactions in cilia using CRISPR/CAS9, cryo-ET, and mass spectrometry, revealing a complex involving FAP263, FAP78, FAP184, and FAP151, and links it to dynein f phosphorylation.