Charlotte de Ceuninck van Capelle

The paper identifies complex protein network disruptions in human motile cilia from PCD patients using cryo-ET and proteomics, revealing differences from Chlamydomonas.

This paper enhances the spatial resolution of soft X-ray tomography using physics-aware learning, improving structural fidelity and reducing radiation exposure.

This paper introduces a self-supervised model to correct missing wedge artifacts in soft X-ray tomography, improving volume quantification and morphology accuracy in cellular structures.

The paper compares proteomic and structural differences in cilia from PCD patients with DNAH5 mutations, showing patient-specific reductions in ciliary components and structural changes in the axoneme.

This study shows that KNL-1 and the NDC-80 complex are essential for proper axonal organization in C. elegans, revealing a non-canonical role for the KMN network in nervous system development.