Bayesian reassessment of the epigenetic architecture of complex traits
Daniel Trejo Baños, Daniel L. McCartney, Tom Battram, Gibran Hemani, Rosie May Walker, Stewart W. Morris, Qian Zhang, David John Porteous, Allan F. McRae, Naomi R. Wray, Peter M. Visscher, Chris Haley, Kathryn Louise Evans, Ian J. Deary, Andrew Mark McIntosh, , Matthew R. Robinson
This paper introduces a Bayesian method to estimate epigenetic associations with complex traits, finding that methylation data captures significant variance in BMI and smoking behavior.
bioRxiv · Nov 14, 2018 · PreprintGenomics