Author

Tomas Lopes

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Kaitlin N. Girardini· 2 shared Kevon O. Afriyie· 2 shared Kyle D. DrakeiD· 2 shared Rahul KanadiaiD· 2 shared Saren M. SpringeriD· 2 shared Abigail Boria· 1 shared Isabella Stevens· 1 shared Nicolás Camacho· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Kaitlin N. Girardini

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

WATER reveals heterochrony of molecular programs underlies developmental failure caused by minor spliceosome inhibition

Saren M. Springer, Abigail Boria, Kyle D. Drake, Kevon O. Afriyie, Kaitlin N. Girardini, Taveena Konakanchi, Isabella Stevens, Nicolás Camacho, Tomas Lopes, Rahul Kanadia

The paper introduces WATER, a method to analyze temporal gene expression, and shows that minor spliceosome inhibition disrupts developmental timing by redistributing molecular programs.

bioRxiv · May 13, 2026 · PreprintDevelopmental Biology

Integrated multi-omics reveals minor spliceosome inhibition causes molecular stalling and developmental delay of the mouse forelimb.

Kyle D. Drake, Saren M. Springer, Kevon O. Afriyie, Tomas Lopes, Kaitlin N. Girardini, Rahul Kanadia

The paper shows that minor spliceosome inhibition in mouse forelimbs causes transcriptomic stalling and developmental delay, leading to micromelia while maintaining segmentation.

bioRxiv · Nov 10, 2022 · PreprintDevelopmental Biology