Author

Tony Roenspies

Ottawa Hospital Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 4

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Organism:C. elegans· 4 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:dimensionality reduction· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Antonio ColavitaiD· 4 shared Chloe B. Kirezi· 2 shared Clover StubbertiD· 2 shared Nathaniel NoblettiD· 2 shared Pavak Kirit ShahiD· 2 shared Saber Saharkhiz· 2 shared Stéphane FlibotteiD· 2 shared Theodore J. PerkinsiD· 2 shared

Activity by Year

2024-2025 · peak 3/yr

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10 top collaborators · 36 mutual co-author links

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4 shared papersDevelopmental Biology

Antonio ColavitaORCID

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4 papers

Recent·Most cited

Nuclear hormone receptor regulation of PAL-1/Caudal mediates ventral nerve cord assembly in C. elegans.

Nathaniel Noblett, Tony Roenspies, Stéphane Flibotte, Antonio Colavita

The paper identifies a regulatory network involving SEX-1 and PAL-1 in C. elegans ventral nerve cord development, showing their roles in motor neuron positioning.

Developmental Biology · Sep 1, 2025Peer-reviewedDevelopmental Biology

VNC-Dist: A machine learning-based semi-automated pipeline for quantification of neuronal positioning in the C. elegans ventral nerve cord

Saber Saharkhiz, Wesley Chan, Chloe B. Kirezi, Mearhyn Petite, Tony Roenspies, Theodore J. Perkins, Antonio Colavita

VNC-Dist quantifies neuronal positioning in C. elegans VNC using machine learning, improving efficiency and accuracy over manual methods.

PLoS ONE · Aug 28, 2025Peer-reviewedDevelopmental Biology

Notch-dependent left-right asymmetry in β-catenin-TCF activity instructs anteroposterior positioning of motor neurons in the C. elegans ventral nerve cord

Wesley Chan, Evans Justin, Saber Saharkhiz, Clover Stubbert, Elicia Preston, Jonathan D. Rumley, Tony Roenspies, Pavak Kirit Shah, John I. Murray, Theodore J. Perkins, Antonio Colavita

bioRxiv · Mar 2, 2025 · PreprintDevelopmental Biology

IPPK-1 and IP6 contribute to ventral nerve cord assembly in C. elegans

Nathaniel Noblett, Tony Roenspies, Chloe B. Kirezi, Clover Stubbert, Stéphane Flibotte, Pavak Kirit Shah, Antonio Colavita

This study shows that IPPK-1 and IP6 are critical for ventral nerve cord assembly in C. elegans, with IP6 rescue of mutant defects.

bioRxiv · Mar 3, 2024Developmental Biology