Author

Toon Santermans

KU Leuven

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Systems Biology· 1

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Organism:C. elegans· 1 Approach:statistical model· 1

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Alyson W. MacInnesiD· 1 shared Georges E. JanssensiD· 1 shared Marco Lezzerini· 1 shared Marte MolenaarsiD· 1 shared Riekelt H. HoutkooperiD· 1 shared Rob JelieriD· 1 shared

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Alyson W. MacInnesORCID

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Recent·Most cited

Mitochondrial ubiquinone-mediated longevity is marked by reduced cytoplasmic protein translation

Marte Molenaars, Georges E. Janssens, Toon Santermans, Marco Lezzerini, Rob Jelier, Alyson W. MacInnes, Riekelt H. Houtkooper

This study shows that clk-1 mutations in C. elegans extend lifespan by repressing cytoplasmic protein translation, similar to insulin signaling reductions, and identifies TAF-4 as a repressor of polyribosome formation under these conditions.

bioRxiv · Apr 26, 2018 · PreprintSystems Biology