Rob Jelier

The paper investigates the morphogenetic events during early foregut development in the mouse embryo, revealing a coordinated geometric process involving apoptosis and BMP2 signaling.

The paper shows how a duplicated tRNA synthetase evolved into a novel toxin by losing its ancestral function and acquiring a new role in targeting Aurora kinase A.

The paper develops a 3D mechanical model of C. elegans zygote polarization, showing how nematic cortical structures ensure robust axis alignment during polarization.

The paper integrates biomechanical modeling with imaging data to analyze the mechanics of cell ingression during C. elegans gastrulation, showing apical constriction and coordinated cell divisions drive the process.

The paper introduces a method to infer forces from microscopy images of C. elegans embryos, validated by laser ablation, to study morphogenesis.

The paper introduces FlowShape, a framework for analyzing cell shapes using spherical harmonics decomposition, and applies it to study shape changes in C. elegans embryos.

The paper identifies neuromedin U (NMU) signaling as critical for memory retrieval of learned salt avoidance in C. elegans, showing its role in modulating navigational strategies through specific neurons.

This study shows that clk-1 mutations in C. elegans extend lifespan by repressing cytoplasmic protein translation, similar to insulin signaling reductions, and identifies TAF-4 as a repressor of polyribosome formation under these conditions.