Endothelial Knockdown of the Tumor Suppressor, WWOX, Increases Inflammation in Ventilator-Induced Lung Injury
Zhenguo Zeng, Eltyeb Abdelwahid, Weiguo Chen, Christian Ascoli, Trinh T. Pham, Jeffrey R. Jacobson, Steven M. Dudek, Viswanathan Natarajan, C. Marcelo Aldaz, Roberto F. Machado, Sunit Singla
This study shows that knocking down WWOX in endothelial cells increases inflammation in ventilator-induced lung injury through zyxin upregulation and MAPK signaling changes.
American Journal of Physiology-Lung Cellular and Molecular Physiology · Apr 2, 2024Peer-reviewedMolecular Biology