Steven M. Dudek

The paper creates a database of ACE variants linked to Alzheimer's disease, estimates their population frequency, and links them to reduced blood ACE levels.

This study identifies PMNcyto as a functional cell type generated post-vital NETosis that actively kills bacteria and reduces pneumonia-induced mortality.

This study shows that endothelial ERG regulates neutrophil transcriptome to create an anti-inflammatory vascular niche, preventing excessive inflammation.

This study shows that knocking down WWOX in endothelial cells increases inflammation in ventilator-induced lung injury through zyxin upregulation and MAPK signaling changes.

This study shows that cigarette smoke and e-cigarette vapor reduce WWOX expression in lungs, leading to increased ARDS severity in mice.