ImmunologyiSciencePeer-reviewed
BCL6 in T cells promotes type 1 diabetes by redirecting fates of insulin-autoreactive B lymphocytes
Landon M. Clark, James McAninch, Dudley H. McNitt…·Rachel H. Bonami
This paper shows that BCL6 in T cells promotes type 1 diabetes by enabling anti-insulin B cells to become pathogenic, and that blocking BCL6 in T cells prevents diabetes even when insulin-reactive B cells are present.
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