Author

Tzyy-Jye Doong

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Arletta Lozanski· 1 shared Courtnee A. CloughiD· 1 shared Daniel T. StarczynowskiiD· 1 shared Emma E. UibleiD· 1 shared Erin K. HertleiniD· 1 shared Gerard LozanskiiD· 1 shared Hans Christian ReinhardtiD· 1 shared Jennifer Yeung· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Arletta Lozanski

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1 paper

Recent·Most cited

MYD88 mutations in clonal hematopoiesis promote inflammation and hematopoietic stem cell expansion

Jennifer Yeung, Sophia Y Philbrook, Emma E. Uible, Lynn H. Lee, Kwangmin Choi, Puneet Agarwal, Courtnee A. Clough, Pravin Patel, Kathryn A. Wikenheiser‐Brokamp, Kathleen M. Hueneman, Hans Christian Reinhardt, Tzyy-Jye Doong, Arletta Lozanski, Gerard Lozanski, Tamanna Zohra Haque, , Daniel T. Starczynowski

This study shows MYD88 mutations in clonal hematopoiesis drive inflammation and HSPC expansion by activating NF-κB pathways and promoting myeloid bias.

bioRxiv · Jun 19, 2025 · PreprintCancer Biology